Welcome to TERMIS workshop 2021, Brno, March 5 – 6, 2021!
The International Clinical Research Center of St. Anne University Hospital, Brno, and Masaryk University are pleased to announce the TERMIS workshop: "Cell-Matrix Interaction and Mechanobiology in Regenerative Medicine" running between 5. 3. – 6. 3. 2021 in Brno, Czech Republic, the birthplace of modern genetics.      

TERMIS workshop "Cell-Matrix Interaction And Mechanobiology in Regenerative Medicine" aims to bring together students and researchers from a broad range of disciplines with a common focus on mechanobiology and cell-matrix biology applied to organ development, regeneration, and tissue engineering. 

Concise key lectures on important concepts, discoveries, and cutting edge research will be delivered by young and established experts in this quickly growing field. With the stage thus set, an opportunity to present their own research by short lectures will be given to participants, based on the quality of submitted abstracts. The afternoon lectures will be followed by an evening poster session.  The number of available seats is limited to 100. The selection of participants will be based on the “first come, first served” basis. Thanks to supporting from our partners' several travel grants will be awarded to the best abstracts. 
The small number of attendants of the two-day workshop, the downtown location of Mendel’s Museum in historical premises of Augustinian Abbey, and the participatory programme are designed to stimulate networking. We believe that the quality of lectures, conversations over coffee breaks, evening tour of Mendel's museum, and the visit to the demo lab of TESCAN electron microscope company will make attendance of "Cell-Matrix Interaction And Mechanobiology in Regenerative Medicine" workshop enjoyable and rewarding for both budding and established researchers. 

Looking forward to meeting you in Brno! 

Giancarlo Forte 
Workshop Chair

Aleš Hampl
Workshop Chair


  • Abstract submission deadline: December 4, 2020
  • Registration deadline: January 29, 2021
  • Wokshop: March 5 – 6, 2021

Workshop description

While it has been long known that mechanical forces influence cells in tissues,
and tissue themselves change their mechanical properties during development and disease,
the underlying molecular mechanisms remained unexplored until recently.

Mechanobiology, a multidisciplinary field combining biophysics, molecular biology, material science, and mathematical modelling with cell biology, has started bringing the actual molecular mechanisms to light. Ever since it has become increasingly important for the development of new diagnostics, regenerative medicine modalities, disease modelling, and drug delivery.

As the scope of mechanobiology spans multiple scales from studies of mechanical properties of single molecules to the forces acting in whole organs, employs different specialized methods, and range of models, it is challenging for aspiring researchers to get a good overview of the whole field. Our workshop aims to cover several relevant mechano-biological topics on different scales to bring about a bird view of the current state of mechanobiology.

  • Molecular mechanisms of stiffness sensing at the level of membrane, nucleus and membrane.
  • Extracellular matrix (ECM) biology, characterization of its mechanical and biochemical properties during development, health, and disease. 
  • Effects of cell-ECM interaction on cell fate. 
  • Properties of cell-ECM interaction, which can be exploited for drug delivery, 3D disease modelling in vitro, and tissue regeneration. 
  • Use of nanoparticles for drug delivery and cell manipulation. Modelling of tissue dynamics.
We anticipate that participation in the workshop will lead to a broader view of mechanobiology research, cross-disciplinary collaboration among attendees, and shared understanding of the path towards the use of mechanobiology in regenerative medicine.